Speaker
Description
Abstract:
Background: Antibiotic resistance among pathogenic bacteria is a growing global health concern, propting the search for effective and environmentally friendly alternatives to antimicrobial. Silver has been used as an alternative, including in the synthesis of nanoparticles, to treat burns, wounds, and many infections caused by pathogenic bacteria. Objective: This study aimed to biosynthesis silver nanoparticles using Solanum melogena leaf extract and assess their antibacterial activity against selected human pathogens. Methods: Aqueous extracts of sesame plant leaves were prepared and reacted with silver nitrate (AgNO3) solution. The formation of silver nanoparticles (AgNPs) was monitored by opticl color change and characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD) and Atomic force microscopy (AFM). The antibacterial activity of the synthesized nanoparticles against Escherichia coli and Staphylococcus aureus was tested using the agar well diffusion method. Results: the average size of the synthesized silver nanoparticles was verified to be 37.98 nm, confirming that the y were indeed nanoparticles. The antibacterial activity of the synthesized silver nanoparticles was evaluated against both Gram-positive and Gram-negative bacteria, and they were highly against these pathogens. Main Conclusions: S. melogena leaf extract is an effective green agent for synthesizing antibacterial silver nanoparticles with potential biomedical applications.
Keywords: Solanum melongena, Antibacterial activity, Silver nanoparticles.
